Harmonic Bionics – empowering patients with movement disorders through robotics

Harmonic Bionics is developing robotic exoskeletons to improve the lives of individuals suffering from movement impairments due to neurological and musculoskeletal disorders. Harmonics’ flagship product is the Harmony SHR system, a bilateral, upper-extremity exoskeleton. The company recently closed $7M in funding from a Series A round in early May 2021. Funds from the round will support clinical research and scaling of product development for the company’s Harmony SHR system. Key competitors in the robotic exoskeleton market include Ekso Bionics, Fourier, and ReWalk Robotics.

UltraSight raises $13M from Series B round

According to a press release from the company, the investment will be used to support US clinical trials for its guidance platform. UltraSight is developing an artificial intelligence-powered solution to democratize point-of-care cardiac sonography. Traditionally, cardiac sonography requires routine practice for the clinician to maintain proficiency. UltraSight’s platform utilizes machine learning to automatically guide clinicians, regardless of experience through the cardiac sonography process. GE Healthcare, Mindray, and Philips are key strategics developing solutions for the cardiac ultrasound market.

Elucid – predictive image analysis software for future risk of major cardiovascular events

Boston-based Elucid is developing ElucidVivo, an FDA-cleared arterial analysis software solution. The non-invasive test allows clinicians to evaluate key biomarkers to stratify a patient’s risk of major adverse cardiovascular events (e.g. stroke), plan for procedure, and track response to the selected therapeutic approach. ElucidVivo integrates with DICOM images, pathology images, and eCRF solutions. The company recently raised $8M from a Series A round, bringing total funds raised to date to approximately $19.4M.

Vivos Therapeutics – a non-pharmaceutical treatment for obstructive sleep apnea

Vivos Therapeutics has developed the Vivos System, a biomimetic device, similar to a dental retainer, worn during sleep to reshape the upper airway over a 12 to 24 month period. The Vivos System is FDA cleared for the treatment of mild-to-moderate obstructive sleep apnea (OSA), snoring, and sleep-disordered breathing. The company’s technology differs from traditional management options for OSA, including CPAP and surgical implants, in that the Vivos System cures the cause of OSA. Vivos Therapeutics has gone public (NASDAQ:VVOS) and has raised approximately $24M in post-IPO equity.

NuShores Biosciences is developing solutions for bone and tissue regeneration

NuShores Biosciences was formed to commercialize regenerative technologies developed at the University of Arkansas at Little Rock. The company’s lead product, NuCress, is a scaffold-based platform embedded with small amounts of hydroxyapatite (HA) and demineralized bone matrix (DMB). NuCress addresses the limitations of current solutions for major bone injuries by promoting the healing of large segmental bone breaks (>2.5cm). The company has raised approximately $9M in grant research funding to date. The regenerative biomaterials market strategic landscape includes key competitors such as Cerapedics, Mesoblast, and Zimmer Biomet.

Mitre Medical is developing a less invasive surgical solution for mitral valve regurgitation

The company’s Mitral Touch epicardial ring eliminates the need for patients to be on treated without the use of a heart-lung machine (cardiopulmonary bypass). The device is placed around the external surface of the heart to reduce mitral regurgitation (MR) in patients with moderate-to-severe MR. In addition to eliminating the need for cardiopulmonary bypass, the Mitral Touch device enables surgeons to visually confirm MR reduction on a beating heart. Abbott, Edwards Lifesciences, and Medtronic are key strategics developing solutions for the treatment of TMVR.

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